Final ProgramCPSA 2012
Transforming Drug Discovery & Development Through Innovation:
Past, Present and Future
October 1 - 4, 2012
Sheraton Bucks County Hotel
Langhorne, PA
Session Synopsis
Thursday, 10:15 am - 11:45 am
Perspectives on the Quantification of Peptides and Proteins by Mass Spectrometry
Discussion Leader: Susan Abbatiello, The Broad Institute of MIT and Harvard
Peptide and protein quantification is an essential step in establishing drug efficacy, determining the biological variation of a candidate protein biomarker, or in monitoring specific processes in a biochemical pathway. The objective of this session is to evaluate current technologies and how they have been applied to improve sensitivity, accuracy, and precision without sacrificing cost or sample throughput, and how the balance may differ depending on experimental goals.
Presentations:
Exploiting Chemical and Analytical Technologies for Fast, Robust, and Sensitive Quantitation of Peptides and Proteins in Biological Samples
Susan Abbatiello, The Broad Institute of MIT and Harvard
Quantification of Proteins Targeted by Biotherapeutics using Immuno-affinity LC-MS/MS
Mireia Fernandez-Ocaña, Pfizer
Using Mass Spectrometric Immunoassay (MSIA) in Biomarker Development
Randy Nelson, University of Arizona
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