CPSA 2009
Impacting Biology through Analysis
October 26-29, 2009
Langhore, PA
Final Program
Monday, October 26 | |
8:30 pm - 4:30 pm |
Short Courses
Method Development for LC/MS: Traditional Approaches and Emerging Trends
High Throughput Drug Discovery Support: LC/MS Strategies for Method Development, Profiling and Workflow Solutions
Is Poor Bioavailability in Early drug Discovery a Problem and If So, How Can We Solve It?
Analysis of Peptides and Proteins: Sample Preparation to Identification to Quantitation
Small Molecule Structure Elucidation by NMR |
5:30 am - 7:30 pm | Reception & Reigistration |
7:30 am - 10:00 pm | Sponsors Dinner Event |
Tuesday, October 27 | |
7:30 am - 8:30 am | Reigistration & Continental Breakfast |
8:30 am - 8:35 am |
Welcome
|
8:30am - 8:45 am |
Objectives, Format & Opening Remarks
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8:45 am - 9:30 am | Plenary Lecture
The Impact of High-Performance Mass Spectrometry on Biology Research
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9:30 am - 9:45 am | Break / Roundtables |
9:45 am - 11:15 am |
High Performance Workflows: Emerging Applications for Simultaneous Qualitative-Quantitative Analysis
An Automated Multi-Assay Sample Preparation Suite for Regulated Bioanalysis
Characteristics of a Mass Spectrometer Designed to be Optimized for Both Quantitative and Qualitative Bioanalytical Analyses
An Integrated Approach to In Vitro and In Vivo Metabolite Quantitation Based on High Resolution Full Scan MS Data
Hybrid Microfluidics for Sample Processing and Separations
|
11:15 am - 11:30 am | Break / Roundtables |
11:30 pm - 12:45 pm | Complimentary Lunch / Roundtables
Why Biomarkers for Toxicology and Clinical Diagnostics Fail... or Don't Have Broader Acceptance
Use of Mass Spectrometry Based Bioanalytics for Liver Toxicity Biomarker Study
Targeted Biomarker Profiling by LC/MS/MS
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12:45 pm - 3:00 pm |
Poster Session/Rountables |
2:00 pm - 3:00 pm |
Rountable Workshop Sessions High Performance Sample Preparation for the Quantitation of Proteins and Peptides
Discovery to Manufacturing: The Use of Simulated Moving Bed Chromatography ’Äì Orochem Technologies
Advances in Integrated Analysis: From Drug Metabolism to Biological Systems ’Äì Shimadzu
GMP NMR - North Jersey NMR Discussion Group
|
3:00 pm - 4:15 pm |
Small Molecule Biomarker Assay Development and Validation Quantitation of Endogenous Markers in Drug Discovery Validation of Clinical Biomarkers Small Molecule Biomarkers: The Journey From Initial Discovery Through Clinical Utility Validation |
4:15 pm - 4:45 pm | Break / Roundtables |
4:45 pm - 6:00 pm |
Small Interfering RNA and Gene Silencing: Emerging Opportunities for Analysis in Drug Discovery and the Potential of a Bioanalytical Equivalent Bioanalytical Methods and Issues with Antisense Oligonucleotides Strategies and Methods for the LC/MS Analysis of siRNA |
6:00 pm - 8:00 pm |
Sponsor Hospitality - Evening Workshops Microscale LC Advantages for Pharmaceutical Applications: Fast, Robust and Cost-Effective Results - Eksigent Practical Aspects in Quantitating Oligonucleotides by LC/MS Instrument Leasing and Asset Management - McKinley Scientific Advanced Chemistry Development/ACD Labs Vendor Night |
Wednesday, October 28 | |
7:30 am - 8:30 am | Reigistration & Continental Breakfast |
8:30 am - 10:00 am |
Protein Based Biomarkers Differential Mass Spectrometry - A Promising Approach for Biomarker Discovery, Validation, and Qualification Practical Considerations in MRM-Based Assay Development for Peptide Quantitation in Plasma Urinary Biomarkers of Kidney Injury: Evaluation, and Regulatory Approval Process |
10:00 am - 10:30 am | Break / Roundtables |
10:30 am - 12:15 pm |
Tools for Understanding Biology Through Analysis Maximizing Utility of PK/PD Studies during Lead Optimization Using MALDI Imaging Mass Spectrometry for Biomarker Discovery Hurel Static and Flow-Based Systems: Tools for Drug Metabolism and Toxicology |
12:15 pm - 2:15 pm |
Exhibition Open |
1:15 pm - 2:15 pm |
Roundtable Workshop Sessions / Sponsored Lunch Biomarker Identification, Qualification, Validation and Applications - Eurofins Medinet High Performance Nanospray - New Objective Accelerator Mass Spectrometry: High Performance Clinical Development with Microdoses and Microtracers - Vitalea Science |
2:15 pm - 3:30 pm |
Toxicity Markers Metabonomics and Model Characterization as a Foundation for Biomarker Discovery Development and Application of Toxicity Biomarkers |
3:30 pm - 5:30 pm |
Poster Session / Vendor Session |
6:30 pm - 7:30 pm |
Dinner |
7:30 pm - 7:45 pm | Announcements CPSA Shanghai 2010 Introduction CPSA - Distinguished Analytical Scientist Award Presentation Using Mass Spectrometry in New Drug Discovery: Past, Present and Future The Impact of Mass Spectrometry in Pharmaceutical Lead Optimization - Studies on Metabolic Activation |
Thursday, October 29 | |
7:30 am - 8:30 am | Reigistration & Continental Breakfast |
8:30 am - 10:00 am |
Peptide and Protein Quantitation: Are Trypsin and MRM Sufficient? Mass Spectrometric Protein Quantification - The Good, Bad and Ugly Strategies to Improve SRM Selectivity and Alternative Approaches for Proteins and Peptides Quantitation |
10:00 am - 10:30 am | Break / Roundtables |
10:30 am - 12:15 pm |
High Throughput Quantitation: Going Faster by Going Faster and Going Slower Ultra-Fast Chromatography Using Fused-Core Columns To Increase Bioanalytical Throughput Parallel Offline Sample Prep using Electrophoretic Fractionation and Enrichment Laser Diode Thermal Desorption (LDTD) an Alternative to the LC for High-Throughput Quantitation: Some Early Case Studies |
12:15 pm - 2:00 pm | Complimentary Lunch / Roundtables Maintaining our Innovative Fitness during Times of Transition Distributed R&D: Isn't There Something Better than Spreadsheets and eMail? Fostering Automation Implementation through Global Collaboration Wrap Up & Adjourn |